WebThis is attributed to the high hygroscopicity of the amorphous phase and its high water-binding capacity. Under unfavorable ambient conditions, this induces uncontrolled … WebOct 24, 2024 · The decomposition leads to reduced hygroscopicity because of destruction of hydroxyl sites. ... (DVS) apparatus (DVS Intrinsic, Surface Measurement Systems, London, UK). The device produces very accurate sorption isotherms, utilizing a microbalance in a carefully controlled atmosphere of nitrogen and water vapour. About …
DVS Discovery - Surface Measurement Systems
WebThis article is cited by 130 publications. Tze Ning Hiew, Dmitry Y. Zemlyanov, Lynne S. Taylor. Balancing Solid-State Stability and Dissolution Performance of Lumefantrine Amorphous Solid Dispersions: The Role of Polymer Choice and Drug–Polymer Interactions. WebApr 9, 2024 · The DVS results of the above four samples are shown in Figure 9 and Table S5. In compared with MET–RHE, RHE, and MET·HCl, MET has serious hygroscopicity, wherein MET begins to absorb moisture rapidly with the increase in relative humidity. When the relative humidity reached 95%, the weight increase of MET sample reached 49.41%. how do pdf sewing patterns work
(PDF) Hygroscopicity categorization of pharmaceutical solids by
WebNov 5, 2016 · Hygroscopicity study. The solid samples of FUR polymorphs, the supramolecular complexes prepared using KN and their PMs were accurately weighed before storage. The samples were withdrawn at pre-determined intervals (every 30 days) to monitor their weight changes. All these experiments were carried out in triplicate. 3. … WebLab Services: Polymorph, Salt, Cocrystal and Crystallization Screening, Crystallization Process Development, Solid-State Characterization by PXRD, DSC, TGA and DVS (Hygroscopicity Assessment ... Dynamic vapor sorption (DVS) is a gravimetric technique that measures how quickly and how much of a solvent is absorbed by a sample: such as a dry powder absorbing water. It does this by varying the vapor concentration surrounding the sample and measuring the change in mass which this produces. … See more The main application of DVS is to measure water sorption isotherms. In general, a vapor sorption isotherm shows the equilibrium amount of vapor sorbed as a function of steady state relative vapor pressure at … See more Figure 1 shows a typical water sorption result from a DVS experiment for a microcrystalline cellulose sample. The kinetic data (Figure 1a) shows the change in mass and … See more DVS measurement has applications over a wide range of industries. Both equilibrium vapor sorption isotherms and vapor sorption kinetic … See more • Hygroscopy • Moisture sorption isotherm • Water content See more how much protein is needed for the keto diet